Water-tolerant enantioselective carbonyl-ene reactions with palladium(II) and platinum(II) Lewis acid catalysts bearing BINAP

Palladium(II) and platinum(II)-BINAP Lewis acid catalysts have been proved to be water-tolerant in enantioselective carbonyl-ene reactions. The enanitioselective carbonyl-ene reactions of phenylglyoxal monohydrate and 4-methylphenylglyoxal monohydrate with alkenes were investigated demonstrating good to excellent enantioselectivites with e.e. values as high as 95.4%.