Research progress on proton magnetic resonance spectroscopic imaging for monitoring response of neoadjuvant chemotherapy in breast cancer

MR multi-functional imaging techniques, such as MR perfusion weighted imaging, diffusion weighted imaging and spectroscopic imaging, have a important value in breast cancer diagnosis, differential diagnosis and monitoring therapeutic effect of neoadjuvant chemotherapy for breast cancer. This paper is devoted to reviewing the proton-magnetic resonance spectroscopic (1HMRS ) imaging techniques. The basic principle of 1HMRS, commonly used positioning technology and spectral line postprocessing are intruoduced essentially. Present status and progress of the application on 1HMRS in breast cancer diagnosis, differential diagnosis and monitoring therapeutic effect of neoadjuvant chemotherapy for breast cancer are introduced in detail.