Complete cytogenetic remission in a patient with FIP1L1-PDGFRA fusion negative chronic eosinophilic leukemia associated with atypical thrombotic events

Summary We present a rare case of a patient with chronic eosinophilic leukemia, who did not develope the well known organ involvements of the heart, lungs, the skin or nervous system, but who suffered form atypical thrombotic complications including a life threatening sinovenous thrombosis. His disease showed a rapid response to a very low dose of imatinib an the complete remission of a complex cytogenetic abnormality.