Efficient neutralization of anthrax toxin by chimpanzee monoclonal antibodies against protective antigen

The Journal of infectious diseases, Volume 193, Issue 5, 2006, Pages 625-633.

Cited by: 71|Bibtex|Views2|Links
WOS
Keywords:
monoclonal antibody

Abstract:

Four single-chain variable fragments (scFvs) against protective antigen (PA) and 2 scFvs against lethal factor (LF) of anthrax were isolated from a phage display library generated from immunized chimpanzees. Only 2 scFvs recognizing PA (W1 and W2) neutralized the cytotoxicity of lethal toxin in a macrophage lysis assay. Full-length immuno...More

Code:

Data:

Your rating :
0

 

Tags
Comments