A common haplotype of the LBP gene predisposes to severe sepsis

    Critical care medicine, Volume 37, Issue 10, 2009, Pages 2759-2766.

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    Keywords:
    binding proteinshaplotypesstatistical analysisriskcorrelationMore(5+)

    Abstract:

    To investigate whether common variants across the LBP gene contribute to the development of severe sepsis. Sepsis is the leading cause of multiple system organ dysfunction and death in critically ill patients. The lipopolysaccharide-binding protein is an acute-phase protein that plays a dominant role in the genesis of sepsis by initiating...More

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