A phase I trial of 96-hour padlitaxel infusion plus accelerated radiotherapy of unrespectable head and neck cancer

M Machtay,V Aviles,M M Kligerman,J Treat,G S Weinstein,R S Weber,N Mirza,A A Chalian,D I Rosenthal

International Journal of Radiation Oncology*Biology*Physics（1999）

引用 14|浏览5

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摘要

Purpose: To determine the maximum tolerated dose (MTD) of paclitaxel given as a 96-hour continuous infusion during Weeks 1 and 5 of an accelerated radiotherapy schedule for the definitive treatment of advanced (nonmetastatic) unresectable squamous cell carcinoma of the head and neck (SCCHN).

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关键词

Head and neck cancer,Accelerated radiotherapy,Concurrent chemoradiotherapy,Paclitaxel

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