ENSAYO CLíNICO PRáGMATICO EN TRAUMA: EL ESTUDIO CRASh-2 EN EL PERÚ

Alonso Soto,Elfi Torres,José Caballero,Wenceslao Azabache-Puente,César E. Malca-Polo,Marco Gonzáles-Portillo,Diana Rodríguez-Hurtado,Juan Vélez-Temoche,Edgar Núñez-Huerta,Anselmo Moya-Charcape,Jorge Flores del Pozo,Pedro J. Lagos-Poma,Hernán Cruz-Yupanqui,J. Jaime Miranda

Revista Peruana de Medicina Experimental y Salud Pública（2008）

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摘要

CRASH-2 is a pragmatic clinical trial which evaluates the efficacy of a widely available, low cost antifibrinolytic for the prevention of mortality and bleeding in patients with trauma. In this article we present some issues related to the magnitude of the problem as well as the need for research in trauma relevant to the Peruvian context. The rationale for the CRASH-2 trial and the Peruvian experience up to date are also discussed.

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traffic accidents source: decs bireme.,clinical trial,tranexamic acid,antifibrynolitics

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