Modifications de l'excitabilite corticale (frontale et occipitale) par des trans d'eclairs chez le singe Papio papio

The experimental conditions necessary for obtaining an evoked paroxysmal response from the frontal cortex were studied in the baboon Papio papio. The trigger stimulus was comprised of an isolated flash preceded by a train of intermittent light stimulation (SLI). Two conditions were necessary for the appearance of paroxysmal responses: a subconvulsant dose of DL-allyglycine had to be injected at least 3 h previous to recording, and a sufficient number of SLI trains had to be presented to the animal. The paroxysmal responses disappeared as soon as SLI trains were stopped.