Plasma levels of remnant particles are determined in part by variation in the APOC3 gene insulin response element and the APOCI - APOE cluster

Remnant particles of triglyceride-rich lipopro- teins (RLP) are known to be a strong predictor of athero- genicity. The serum concentrations of remnant-like particle triglyceride (RLPTG) and remnant-like particle cholesterol (RLPC) have been determined in a representative sample of the Czech MONICA study (n 5 285). The relationship was investigated between remnant particle triglyceride/ cholesterol concentrations and polymorphisms in the genes APOC3 ( 2 482C