COX-2 gene polymorphisms and protein expression in renomedullary interstitial cell tumors

Human Pathology, pp. 1495-1504, 2008.

Cited by: 13|Views3


Normal medullary interstitial cells regulate blood flow, water and salt absorption, and ultimately blood pressure through synthesis and secretion of prostanoids in which cycloxygenases play the rate-limiting steps. We found that most renomedullary interstitial cell tumors overexpressed cycloxygenase-2 (COX-2), with concomitant expression ...More



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