Diaspirin cross-linked hemoglobin improves oxygen extraction capabilities in endotoxic shock

    Journal of applied physiology (Bethesda, Md. : 1985), Volume 89, Issue 4, 2000, Pages 1437-1444.

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    Abstract:

    We studied the effects of diaspirin cross-linked hemoglobin (DCLHb), a cell-free hemoglobin derived from human erythrocytes, on blood flow distribution and tissue oxygen extraction capabilities in endotoxic shock. Eighteen pentobarbital sodium-anesthetized, mechanically ventilated dogs received 2 mg/kg of E. coli endotoxin, followed by sa...More

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