4,4-Disubstituted cyclohexylamine based CCR5 chemokine receptor antagonists as anti-HIV-1 agents.

Maosheng Duan,Christopher Aquino,George F Dorsey,Robert Ferris,Wieslaw M Kazmierski

Bioorganic & Medicinal Chemistry Letters（2009）

引用 13|浏览22

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摘要

A series of 4,4-disubstituted cyclohexylamine based CCR5 antagonists has been designed and synthesized. Their antiviral structure–activity relationship has been extensively explored.

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关键词

CCR5,4,4-Disubstituted cyclohexylamine,Antagonists,Anti-HIV-1 agents

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