Enhanced Learning and Memory and Altered GABAergic Synaptic Transmission in Mice Lacking the 5 Subunit of the GABAA Receptor

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paired pulse facilitationsynaptic transmissionmouseactive avoid- anceelevated plus maze更多(7+)

摘要

The 5 subunit of the GABAA receptor is localized mainly to the hippocampus of the mammalian brain. The significance of this rather distinct localization and the function of 5-containing GABAA receptors has been explored by targeted disruption of the 5 gene in mice. The 5 / mice showed a significantly improved performance in a water maze m...更多

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