Analysis of the Binary Littermate Data in the One-Way Layout

BIOMETRICAL JOURNAL(2003)

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摘要
In certain experiments with laboratory animals like rodents, it is common to observe the binary littermate data that the fetuses in the same litter provide a set of independent Bernoulli responses conditional on the litter specific abnormal probability. For testing homogeneity of abnormal proportions of several groups, five methods are discussed in the frame of the one-way layout with litter effects. Simulation results show a superiority of the Rao-Scott procedure.
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关键词
beta-binomial distribution,binary data,quasi-likelihood,litter effect,maximum likelihood,method of moments,overdispersion
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