Effectiveness of Switching from Open to Closed Infusion System for Reducing Central Vascular Associated Bloodstream Infections in an Italian Hospital

BACKGROUND/OBJECTIVES: To determine the effect of switching from an open to a closed infusion system (ViafloÒ) on the rate and time to onset of central venous catheter-associated bloodstream infection (CVC-BSI) in four intensive care units (ICUs) of Milan, Italy.