The influence of valve physiology on outcome following aortic valvotomy for congenital bicuspid valve in children: 30-year results from a single institution.

Objective: Aortic valvotomy is widely used for the treatment of congenital aortic stenosis in children. We sought to evaluate whether the predominant post-valvotomy physiology, aortic insufficiency (AI) or aortic stenosis (AS) independently affected patient outcome. Methods: From 1972-2002, 57 children with congenital aortic stenosis underwent valvotomy. We divided age-matched patients with residual lesions based on their predominant pathology into three groups: Group I (n = 14), patients with moderate Al; Group II (n = 14), patients with moderate AS, and Group III (n = 14), patients with combined Al and AS. Fifteen patients with severe Al or mild residual lesions following valvotomy were excluded from analysis. Results: mean freedom from aortic valve replacement (AVR) was 11.2 +/- 1.7 years in Group I and 21.5 +/- 3.9 years in Group II, P = 0.05. AVR was required in 11 patients (79%) in Group I vs. only 5 (36%) in Group II, P = 0.05. Group III was intermediate, with 9 (64%) requiring AVR. At the time of AVR, patients with aortic stenosis had significantly higher fractional shortening % than those with insufficiency or combined lesions, (Group I: 38.2 +/- 7.9 vs. Group II: 46.3 5.5 vs. Group III: 39.2 +/- 3.7, P = 0.007). Patients in Group II also had less severely dilated ventricles (mm) than those in the other groups, (Group I: 50.2 +/- 12.5 vs. Group II: 39.5 +/- 8.3 vs. Group III: 49.0 +/- 8.1, P = 0.030). Conclusions: patients with predominant Al following valvotomy are more likely to need AVR sooner than those with residual. stenosis without Al. Therefore, cautious use of repeat valvotomy using maneuvers to avoid Al (small balloons), may prolong freedom from aortic valve replacement in those patients with significant residual AS. (C) 2004 Elsevier B.V. All rights reserved.