Allergen challenge of peripheral blood mononuclear cells from patients with seasonal allergic rhinitis increases IL-17RB, which regulates basophil apoptosis and degranulation.
CLINICAL AND EXPERIMENTAL ALLERGY（2010）
摘要
Increased expression of IL-17RB on allergen-challenged basophil is regulated by IL-3, inhibits apoptosis and promotes IgE-mediated degranulation of basophils.
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关键词
apoptosis,basophils,degranulation,gene expression microarray,IL-17RB,seasonal allergic rhinitis
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