Effects of the CCR5-Δ32 mutation on antiviral treatment in chronic hepatitis C

Golo Ahlenstiel,Thomas Berg,Rainer P Woitas,Frank Grünhage,Agathe Iwan,Lothar Heß,Hans H Brackmann,Bernd Kupfer,Andrea Schernick,Tilman Sauerbruch,Ulrich Spengler

Journal of Hepatology（2003）

引用 42|浏览10

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摘要

Background/Aims: The CC-chemokine receptor (CCR) 5-Δ32 mutation may predispose to chronic liver disease and high level viremia in hepatitis C. However, it is unclear whether CCR5-Δ32 also affects the response to antiviral treatment.

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关键词

CCR5,Hepatitis C virus,Interferon,Ribavirin,Treatment response

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