Function of a minus-end-directed kinesin-like motor protein in mammalian cells

JOURNAL OF CELL SCIENCE, pp. 4041-4050, 1999.

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Abstract:

CHO2 is a mammalian minus-end-directed kinesin-like motor protein present in interphase centrosomes/nuclei and mitotic spindle fibers/poles. Expression of HA- or GFP-tagged subfragments in transfected CHO cells revealed the presence of the nuclear localization site at the N-terminal tail, This domain becomes associated with spindle fibers...More

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