Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB2 agonists.

Bioorganic & Medicinal Chemistry Letters（2009）

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摘要

A series of novel morpholinomethyl-phenyl amide cannabinoid agonists was developed and their biological activity determined.

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关键词

Cannabinoid CB2 receptor agonist,Selectivity,Structure–activity relationship,Metabolic stability,Antiallodynic activity

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