Benzimidazole-substituted (3-phenoxypropyl)amines as histamine H3 receptor ligands.

Robert Aslanian,Xiaohong Zhu,Henry A Vaccaro,Neng-Yang Shih,John J Piwinski,Shirley M Williams,Robert E West

Bioorganic & Medicinal Chemistry Letters（2008）

引用 17|浏览12

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摘要

A series of non-imidazole histamine H3 receptor antagonists based on the (3-phenoxypropyl)amine motif have been identified. Compound 8a displays a good pharmacokinetic profile in the rat.

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关键词

Histamine,H3

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