On the utility of data from the International HapMap Project for Australian association studies

Jim Stankovich,Charles J. Cox,Rachel B. Tan, Douglas S. Montgomery, Stewart J. Huxtable,Justin P. Rubio,Margaret G. Ehm,Laura Johnson,Helmut Butzkueven,Trevor J. Kilpatrick,Terence P. Speed,Allen D. Roses,Melanie Bahlo,Simon J. Foote

Human Genetics（2006）

引用 17|浏览25

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摘要

We compare patterns of linkage disequilibrium (LD) for 633 SNPs in two regions between samples collected in two Australian states and HapMap samples collected from Utah residents of Northern and Western (NW) European ancestry (CEU). Patterns of LD in the Australian and HapMap samples are similar, and tag SNPs chosen using HapMap genotypes perform almost as well on Australian samples as tags chosen using Australian genotypes.

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关键词

Linkage Disequilibrium,European Ancestry,International HapMap Project,Multiple Sclerosis Case,HapMap Sample

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