Direct chemotactic action of angiopoietin-1 on mesenchymal cells in the presence of VEGF

Microvascular Research, pp. 221-230, 2004.

Cited by: 56|Views3


Angiopoietin-1 (Ang1) and its receptor, Tie2, play an important role in angiogenesis and vessel maturation. We previously reported that overexpression of Ang1 in MCF7 xenograft tumors facilitated vessel stabilization by mural cells, and that cultured SMC express Tie2. Here, we investigated whether Ang1 directly acts as a chemoattractant o...More



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