Natural anticoagulants limit lipopolysaccharide-induced pulmonary coagulation but not inflammation

The European respiratory journal, Volume 30, Issue 3, 2007, Pages 423-428.

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Keywords:
fibrinolysisprotein csepsisacute lung injurycoagulationMore(1+)

Abstract:

Pulmonary coagulopathy and hyperinflammation may contribute to an adverse outcome in sepsis. The present study determines the effects of natural inhibitors of coagulation on bronchoalveolar haemostasis and inflammation in a rat model of endotoxaemia. Male Sprague-Dawley rats were randomised to treatment with normal saline, recombinant hum...More

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