Pregnancy Specific β₁-glycoprotein in Threatened Abortion

The aim of this study was to elucidate the prognostic value of the pregnancy specific β1-glycoprotein (SP-I == PS/βG) of maternal serum in threatened abortion. Determinations were made by rocket-immunoelectrophoresis with a detection limit of I mg/1. 59 patients with vaginal bleeding and positive pregnancy tests entered the final material. 33 gave birth after the 28th week, 26 had a spontaneous abortion. Serum samples were taken until birth or spontaneous abortion. After the 9th gestational week a separation of the serum concentrations was observed between the patients who had a spontaneous abortion and those who gave birth. It is concluded that the SP-1 determination might be of great prognostic value in threatened abortion.