Immunological Analysis ofHostandAgentEffects on Creutzfeldt-Jakob Disease andScrapie PrionProteins

1988.

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Abstract:

Creutzfeldt-Jakob disease (CJD)andscrapie are degenerative neurological diseases caused byunusual infectious pathogens. Thetermprion hasbeenintroduced tounderscore theapparent distinctness ofthese agents fromviruses andviroids. Theonlymacromolecule showntobeassociated withtheinfectious agent, the CJDorscrapie prion protein (PrPCJD orPrPSc...More

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