Detection of Chromosomal Aberrations by a Whole-Genome Microsatellite Screen

AMERICAN JOURNAL OF HUMAN GENETICS, pp. 419-427, 2000.

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Abstract:

Chromosomal aberrations are a common cause of multiple anomaly syndromes that include developmental and growth retardation. Current microscopic techniques are useful for the detection of such aberrations but have a limit of resolution that is above the threshold for phenotypic effect. We hypothesized that a genomewide microsatellite scree...More

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