Commonly used cat reporter vectors contain a cAMP-inducible, cryptic enhancer that co-operates with NF-KB-sites

Commercially available and widely used cat expression vectors were found to contain a forskolin (Fs) -inducible element capable of co-operation with NF-KB-sites in test promoters. An alternative NF-κB-dependent reporter system is presented that allows investigation of the effects of Fs and other agents that augment intracellular cyclic AMP.