Histopathological lesions following intramuscular administration of saline in laboratory rodents and rabbits.
Experimental and Toxicologic Pathology(2009)
摘要
This review was undertaken to assess the nature and incidence of procedure-related changes in mice, rats and rabbits which received saline solution by intramuscular injection. Data were collected on the injection sites from 7 studies representing 152 animals. The original observations by the different study pathologists from both control and treated animals were evaluated in order to create a glossary of preferred terms to be used in toxicology studies.
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关键词
Intramuscular administration,Saline,Intramuscular lesions,Mouse,Rat,Rabbit,Toxicology
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