The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated with thrombin or calcium ionophore A23187.

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL(2009)

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关键词
enzyme activation,caspase 3,blood platelets,apoptosis,flow cytometry
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