Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors.
Bioorganic & Medicinal Chemistry Letters（2008）
摘要
Phenanthrene imidazole 3 has been identified as a novel potent, selective, and orally active mPGES-1 inhibitor.
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关键词
mPGES-1,PGE2,Inflammation,Prostanoid
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