Previously infected chimpanzees are not consistently protected against reinfection or persistent infection after reexposure to the identical hepatitis C virus strain

    Journal of virology, Volume 82, Issue 16, 2008, Pages 8183-8195.

    Cited by: 71|Bibtex|Views3|Links
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    Keywords:
    open reading framesnucleotidesamino acid sequenceimmune systemgenotype

    Abstract:

    Protective immunity after resolved hepatitis C virus (HCV) infection has been reported. However, the breadth of this immunity has remained controversial, and the role of neutralizing antibodies has not been well-defined. In the present study, two chimpanzees (CH96A008 and CH1494) with resolved monoclonal H77C (genotype 1a) infection were ...More

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