High-Frequency Components Of Auditory Evoked Potentials Are Detected In Responsive But Not In Unconscious Patients
European Journal of Anaesthesiology(2005)
摘要
Background: The dose-dependent suppression of midlatency auditory evoked potentials by general anesthetics has been proposed to measure depth of anesthesia. In this study, perioiperatively recorded midlatency auditory evoked potentials were analyzed in a tine-frequency space to identify significant changes induced by general anesthesia.Methods: Perioperatively recorded auditory evoked potentials of 19 patients, recorded at varying levels of anesthesia, were submitted to a multiscale analysis using the wavelet analysis. Energy contents of the signal were calculated in frequency bands 0 - 57.1 Hz, 57.1 - 114.3 Hz, 114.3 - 228.6 Hz, and 228.6 - 457.1 Hz. A Friedman test and a Dunn multiple comparisons test were performed to identify significant differences.Results: Statistical evaluation showed a highly significant decrease of the wavelet energies for the frequency bands 57.1 - 114.3 Hz (P < 0.0001), 114.3 - 228.6 Hz (P < 0.0001), and 228.6 - 457.1 Hz (P < 0.0001) for the measuring points representing deep general anesthesia. This decrease is accompanied by a decrease in the wavelet energy of the frequency band 0-57.1 Hz of no statistical significance (P = 0.021) (level of significance set to P = 0.01). The changes are most prominent In the poststimulus interval between 10 and 30 ms.Conclusions: This study describes die presence of high-frequency components of the auditory evoked potential. The amount of these components is higher during responsiveness when compared to unconsciousness. Temporal localization of the high-frequency components within the auditory evoked potential shows that they represent a response to the auditory stimulus. Further studies are required to identify the source of these high frequency components.
更多查看译文
关键词
high frequency,anesthesia
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要