The mouse Pol I terminator is more efficient than the hepatitis delta virus ribozyme in generating influenza-virus-like RNAs with precise 3' ends in a plasmid-only-based virus rescue system

    Archives of virology, Volume 154, Issue 7, 2009, Pages 1151-1156.

    Cited by: 12|Bibtex|Views1|Links
    WOS SCOPUS
    Keywords:
    reverse geneticsrnacell linesplasmids

    Abstract:

    Reverse genetics systems for generating recombinant influenza viruses are based on two different mechanisms for obtaining the 3' end of the viral RNA: one uses the self-cleaving hepatitis delta virus ribozyme (HDVR), and the other uses the murine RNA polymerase I (Pol I) terminator. In this study, we employed EGFP and Renilla luciferase r...More

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