Synthesis and regioselective alkylation of 1,6- and 1,7-naphthyridines

TETRAHEDRON LETTERS(2000)

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摘要
A regioselective alkylation of naphthyridines 4a-d, through the action of ethylchloroformate and benzylstannane 5, afforded the benzyl substituted dihydronaphthyridines 3a-d. These key intermediates 3a-d were transformed into the desired targets 2a-d in seven steps. (C) 2000 Elsevier Science Ltd. All rights reserved.
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