Biodistribution of 99mTc-HYNIC-lactadherin in mice--a potential tracer for visualizing apoptosis in vivo.

Lise Falborg,Lasse N Waehrens,Jan Alsner,Henrik Bluhme,Jørgen Frøkiaer,Christian W Heegaard,Michael R Horsman,Jan T Rasmussen,Michael Rehling

SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION（2010）

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摘要

In conclusion, the biodistribution of (99m)Tc-HYNIC-lactadherin, a potential new tracer for in vivo quantification of apoptosis, was evaluated. The small renal uptake of (99m)Tc-HYNIC-lactadherin makes it possible to image apoptosis in the kidneys, but the high liver clearance may be a disadvantage during myocardial perfusion.

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