Parathyroid hormone induced stimulation of calcium uptake by renal microsomes.

Cortical and papillary microsomes prepared from feline kidneys perfused with parathyroid hormone (PTH) showed an enhanced ability to accumulate calcium (Ca +2 ). PTH was unable to stimulate Ca +2 uptake into microsomes prepared from outer medulla. These data suggest that renal microsomes may be a valid model system for studying the action of PTH on Ca +2 transport in the kidney.