Microwave-Assisted Aminocarbonylation of Aryl Bromides at Low Carbon Monoxide Pressure

An efficient and rapid procedure for microwave-assisted aminocarbonylation of aryl bromides and iodides at low CO pressure, using (PPh3)(2)PdCl2 or Pd(OAc)(2) as catalysts is reported. Different reaction conditions have been tested in order to carry out the reaction even on less nucleophilic anilines such as 2-chloro-4-nitroaniline, allowing a rapid access (in 20-30 min) to several diverse arylamides in good yields.