ChemInform Abstract: Synthesis and Monoamine Transporter Affinity of 3β-(4-(2-Pyrrolyl)phenyl)-8-azabicyclo[3.2.1]octanes and 3β-(5-Indolyl)-8-azabicyclo[3.2.1]octanes.

Huw M. L. Davies,Pingda Ren,Norman Kong,Tammy Sexton,Steven R. Childers

Cheminform（2010）

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摘要

3β-(5-Indolyl)-8-azabicyclo[3.2.1]octanes display potent binding affinity for both the dopamine and serotonin transporters, while certain 3β-(4-(2-pyrrolyl)phenyl)-8-azabicyclo[3.2.1]octanes selectively bind to the serotonin transporter.

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monoamine transporter affinity,synthesis,cheminform abstract

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