Fine mapping in 94 inbred mouse strains using a high-density haplotype resource

Genetics, Volume 185, Issue 3, 2010, Pages 1081-1095.

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Keywords:
genomehaplotypeslinkage disequilibriumphenotypegenotype

Abstract:

The genetics of phenotypic variation in inbred mice has for nearly a century provided a primary weapon in the medical research arsenal. A catalog of the genetic variation among inbred mouse strains, however, is required to enable powerful positional cloning and association techniques. A recent whole-genome resequencing study of 15 inbred ...More

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