Hepatocyte Growth Factor Increases Glucagon Immunoreactivity In Jejunal Cells During Intestinal Adaptation - Discussion

Our data suggest that the HGF-induced increase in glucagon availability is disassociated from glucagon gene up-regulation. Thus, HGF may not only enhance intestinal adaptation directly, but also indirectly by increasing the "local" availability of other growth factors in the absence of their gene up-regulation.