Ultradian rhythms in the N1-P2 amplitude of the visual evoked potential in two inbred strains of mice: DBA/2J and C57BL/6.

Ultradian rhythmicity has been showed in many behavioural parameters in animals as well as in humans. We investigated the existence of a Basic Rest-Activity Cycle (BRAG) rhythm in amplitude fluctuations of mice's visual evoked potential (VEP) primary component. Two inbred strains of mice, C57BL/6 and DBA/2J, were used to verify the influence of genetics on biological rhythm as well. Results revealed the existence of an evident rhythm in the parameter under study and confirm previous reports of a 20 min. BRAG in avoidance behavior in DBA mice. This rhythm shows similar period within each strain, but significatively different periods between strains. Observed periods are near to species-specific reported BRAG cycle. Genetic hypothesys is suggested to explain differences between strains in expression of ultradian rhythm.