Coexistence Of Chronic Myelogenous Leukemia And Multiple Myeloma - Case Report And Review Of The Literature
ACTA HAEMATOLOGICA(1998)
摘要
A case report of simultaneous presentation of chronic myelogenous leukemia (CML) and multiple myeloma (MM) in a 72-year-old female is described. Our case was typical of Ph-1-positive and chimeric bcr-abl messenger RNA-positive CML. Furthermore, a marked IgG (kappa-type) paraproteinemia was present. Fluorescence in situ hybridization showed that 97% of marrow nucleated cells were positive for bcr-abl fusion signal, when myeloma cells in the bone marrow amounted to 19.0%. In the literature survey, 4 similar cases with coexistence of CML and MM have been identified.
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关键词
chronic myelogenous leukemia, IgGK-type paraproteinemia, multiple myeloma
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