Regioselective Aminomethylations of Bicyclic Phenols

Jos H. M. Lange,Sonja Hoogeveen,Willem Veerman,Henri Wals

HETEROCYCLES（2000）

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摘要

The regioselectivity in the aminomethylations (the Mannich reaction) of bicyclic phenols has been studied. Highly regioselective Mannich reactions enable easy synthetic access to novel bicyclic dialkylaminomethylphenols under very mild reaction conditions.

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