A functional screen for genes inducing epidermal growth factor autonomy of human mammary epithelial cells confirms the role of amphiregulin

    Oncogene, Volume 20, Issue 30, 2001, Pages 4019-4028.

    Cited by: 26|Bibtex|Views2|Links
    WOS NATURE
    Keywords:
    ONC oncogenes cancer apoptosis tumor suppressor genesMore(6+)

    Abstract:

    To gain better understanding of the molecular alterations responsible for the aggressive growth potential of epidermal growth factor receptor (EGFR)-positive breast cancers, we utilized an expression cloning strategy to seek gene products that mediate the EGF-independent growth of human breast cancer cells. A retroviral cDNA expression li...More

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