Dna Vaccine Encoding L7/L12-P39 Of Brucella Abortus Induces Protective Immunity In Balb/C Mice

CHINESE MEDICAL JOURNAL(2006)

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摘要
Live attenuated vaccines can stimulate strong CMI response, which are usually very effective against brucellosis and are used to control brucellosis in domestic animals. However, there is no safe and effective vaccine available for human because the vaccine strains used for animals are considered too virulent for humans. A vaccine that will be noninfectious to humans but ef fective in stimulating a broad protective immune response is needed.
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关键词
Brucella abortus, DNA vaccine, fusion protein
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