Design and structure-activity relationship of heterocyclic analogs of 4-amino-3-benzimidazol-2-ylhydroquinolin-2-ones as inhibitors of receptor tyrosine kinases.
Bioorganic & Medicinal Chemistry Letters（2006）
摘要
The synthesis and SAR of a series of novel heterocyclic analogs of the 4-amino-3-benzimidazol-2-ylhydroquinolin-2-one scaffold are reported.
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关键词
Vascular endothelial growth factor (VEGF),Basic fibroblast growth factor (bFGF),Platelet derived growth factor (PDGF)
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