Clinical and therapeutic implications of hepatitis C virus compartmentalization.

Gaëtana Di Liberto,Anne-Marie Roque-Afonso,Rachid Kara,Delphine Ducoulombier,Guillaume Fallot,Didier Samuel,Cyrille Feray

Gastroenterology（2006）

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摘要

A significant proportion of patients with hepatitis C are co-infected by 2 or more HCV variants with distinct IRES sequences and distinct cellular tropism. This compartmentalization is a strong independent predictor of treatment efficacy.

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关键词

BMC,HVR,IRES,PCR,SSCP,SVR,UTR

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