Diagnostic value of outcome measures following allergen exposure in an environmental challenge chamber compared with natural conditions.

J M Hohlfeld,T Holland-Letz, M Larbig, M Lavae-Mokhtari, E Wierenga, M Kapsenberg,R van Ree,N Krug,A Bufe

CLINICAL AND EXPERIMENTAL ALLERGY（2010）

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摘要

The high reproducibility and sensitivity/specificity in the ECC suggests that TNSS is a valuable outcome measure. While exhaled NO can be considered to monitor airway inflammation, nasal NO appears to be unspecific.

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关键词

allergic rhinitis,biomarker,controlled clinical trial,environmental challenge chamber,exhaled nitric oxide,grass pollen,repeatability,reproducibility,sensitivity,specificity

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