A novel and critical role for Oct4 as a regulator of the maternal-embryonic transition

PloS one, Volume 3, Issue 12, 2008, Pages e4109-e4109.

Cited by: 68|Views6
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Abstract:

Compared to the emerging embryonic stem cell (ESC) gene network, little is known about the dynamic gene network that directs reprogramming in the early embryo. We hypothesized that Oct4, an ESC pluripotency regulator that is also highly expressed at the 1- to 2-cell stages in embryos, may be a critical regulator of the earliest gene netwo...More

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